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Semiconductor Nanocrystals as Fluorescent Biological Labels
Semiconductor nanocrystals were prepared for use as fluorescent probes in biological staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have a narrow, tunable, symmetric emission spectrum and are photochemically stable. The advantages of the broad, continuous excitation spectrum were demonstrated in a dual-emission, single-excitation labeling experiment on mouse fibroblasts. These nanocrystal probes are thus complementary and in some cases may be superior to existing fluorophores.
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“Semiconductor Nanocrystals as Fluorescent Biological Labels” is a paper by Marcel P. Bruchez Mario M. Moronne Peter Gin Shimon Weiss A. Paul Alivisatos published in 1998. It has an Open Access status of “closed”. You can read and download a PDF Full Text of this paper here.